Chronic maxillary osteomyelitis secondary to chronic maxillary sinusitis in non-immunocompromised patient – a rare case report and its management

Osteomyelitis is an inflammation of medullary portion of bone along with cortex and periosteum. It is one of most difficult infectious diseases to treat. Facial bones are prone to osteomyelitis due to various predisposing condition. Osteomyelitis of maxilla is rare disease and less frequently encountered. Objective: The aim of the article is to present an unusual case of chronic maxillary osteomyelitis secondary to rhinogenic which are rarely clinically causes. Case report: We hereby report a case of chronic maxillary osteomyelitis in 70-year-old non-immunocompromised patient secondary to chronic maxillary sinusitis. Complete resolution of chronic maxillary osteomyelitis was achieved by combination of antimicrobial therapy and surgical treatment. Conclusion: Clinician should identify such risk and provide the aggressive treatment modalities to avoid subsequent dreaded consequences.Osteomyelitis is an inflammation of medullary portion of bone along with cortex and periosteum. It is one of most difficult infectious diseases to treat. Facial bones are prone to osteomyelitis due to various predisposing condition. Osteomyelitis of maxilla is rare disease and less frequently encountered. Objective: The aim of the article is to present an unusual case of chronic maxillary osteomyelitis secondary to rhinogenic which are rarely clinically causes. Case report: We hereby report a case of chronic maxillary osteomyelitis in 70-year-old non-immunocompromised patient secondary to chronic maxillary sinusitis. Complete resolution of chronic maxillary osteomyelitis was achieved by combination of antimicrobial therapy and surgical treatment. Conclusion: Clinician should identify such risk and provide the aggressive treatment modalities to avoid subsequent dreaded consequences

Mapping the Research Productivity of Three Medical Sciences Journals Published in Saudi Arabia: A Comparative Bibliometric Study

Introduction: The purpose of this study was to compare the progress of research outcomes specifically of three old and new established Saudi medical research journals: Saudi Journal of Medicine and Medical Sciences (SJMMS), Journal of Saudi Heart Association (JSHA), and Journal of Infection and Public Health (JIPH) for the period of 2013 to 2017. Materials and Methods: Scientific papers under the titles of original and review articles, short communications, case and short reports were downloaded from the websites of these journals. The data was analyzed according to three parameters: the growth of publication, the types of publication, and the authorship pattern. Results: The findings of the study revealed that 827 articles were contributed by 3808 authors with an average of 4.6 authors per article, and 12.9% articles were published in 64 issues of SJMMS (n=600, 15.7%) , JSHA (n=951, 24.9%), and JIPH (n=2257, 59.2%) during 2013–2017. The majority of articles (n=746, 90.2%) included more than one author, leaving only 81 articles (9.7%) were prepared by single (or solo) authors. The authors have been collaborated with national and international authors for their scholarly work. Conclusions: The comparison of bibliometric indicators of the three medical journals showed the rising tendency of research publications and the high rate of collaborative research output. These journals contributed a massive number of research papers during the period of five years. Collaboration among researchers facilitates sharing knowledge and techniques and brings a mixture of positive scientific thoughts. The unified bylaws for faculty in Saudi universities should give more weight to multi-authored papers

Design of neuro-computing paradigms for nonlinear nanofluidic systems of MHD Jeffery–Hamel flow

© 2018 Taiwan Institute of Chemical Engineers In this paper, a neuro-heuristic technique by incorporating artificial neural network models (NNMs) optimized with sequential quadratic programming (SQP) is proposed to solve the dynamics of nanofluidics system based on magneto-hydrodynamic (MHD) Jeffery–Hamel (JHF) problem involving nano-meterials. Original partial differential equations associated with MHD–JHF are transformed into third order ordinary differential equations based model. Furthermore, the transformed system has been implemented by the differential equation NNMs (DE-NNMs) which are constructed by a defined error function using log-sigmoid, radial basis and tan-sigmoid windowing kernels. The parameters of DE-NNM of nanofluidics system are optimized with SQP algorithm. To illustrate the performance of the proposed system, MHD–JHF models with base-fluid water mixed with alumina, silver and copper nanoparticles for different Hartman numbers, Reynolds numbers, angles of the channel and volume fractions with three different proposed DE-NNMs are designed to evaluate. For comparison purpose, the proposed results with reference numerical solutions of Adams solver illustrate their worth. Statistical inferences through different performance indices are given to demostrate the accuracy, stability and robustness of the stochastic solvers

Integrated computational intelligent paradigm for nonlinear electric circuit models using neural networks, genetic algorithms and sequential quadratic programming

© 2019, Springer-Verlag London Ltd., part of Springer Nature. In this paper, a novel application of biologically inspired computing paradigm is presented for solving initial value problem (IVP) of electric circuits based on nonlinear RL model by exploiting the competency of accurate modeling with feed forward artificial neural network (FF-ANN), global search efficacy of genetic algorithms (GA) and rapid local search with sequential quadratic programming (SQP). The fitness function for IVP of associated nonlinear RL circuit is developed by exploiting the approximation theory in mean squared error sense using an approximate FF-ANN model. Training of the networks is conducted by integrated computational heuristic based on GA-aided with SQP, i.e., GA-SQP. The designed methodology is evaluated to variants of nonlinear RL systems based on both AC and DC excitations for number of scenarios with different voltages, resistances and inductance parameters. The comparative studies of the proposed results with Adam’s numerical solutions in terms of various performance measures verify the accuracy of the scheme. Results of statistics based on Monte-Carlo simulations validate the accuracy, convergence, stability and robustness of the designed scheme for solving problem in nonlinear circuit theory

Knowledge, attitudes and practices study of dengue viral infection and its association with environmental factors and health issues, Lahore Pakistan

This study was designed to assess and compare the awareness, approach, and practices of dengue positive and dengue negative patients regarding dengue fever in a tertiary care hospital of Lahore district, Pakistan from April to May 2012. A total of 250 samples (125 dengue positive and 125 dengue negative) were collected and tested for Dengue IgM and IgG antibodies test by ELISA technique. Pretested questionnaire was used for data collection after the informed consent of the patients. Out of 250 study participants, 78% stated fever as major symptom of dengue virus, 70% had knowledge about the vector, 76% had idea about mosquitoes breeding sites and 80% considered dengue a treatable disease. For 50%, the main source of information about dengue was their TV/Radio. Regarding preventive practices, out of 80% who stored water at home, 52% used to cover their water containers, 64% used to wear protective clothing and 22% used mosquito repellents. Overall, 32% were satisfied from Governmental efforts against the spread of dengue fever. The study indicated that the community was quite familiar with Dengue, but there were some confusion about vaccination and water storage for domestic use.Key words: Dengue fever, knowledge, attitudes, environment, IgM, IgG

Effect of Ocimum tenuiflorum Leaf Extract against Infective Endocarditis

The ever increasing resistance of pathogens to antibiotics as well as the undesirable side effects of certain antimicrobial agents has necessitated the discovery of novel natural products. The ethanolic extract of O. tenuiflorum was investigated against S. aureus isolate which is a major pathogen causing infective endocarditis. The total phenolic content in O. tenuiflorum was found to be 1289 μg gallic acid equivalent/g and HPLC profile revealed the presence of catechin, Caffeic acid and p-coumaric acid. The antibacterial profile of O. tenuiflorum against S. aureus isolate from infective endocarditis patients exhibited significant inhibition at the MIC of 50 μg/ml and the standard antibiotic Vancomycin showed inhibition at 40 ng/ml. Percent inhibition of viable growth was found to be >95% and the scanning electron micrographs (SEM) revealed the disruption of the membrane of S. aureus treated with O. tenuiflorum extract. The antimicrobial activity correlates with phenolic content of the extract. These results demonstrate the potency of O. tenuiflorum, could serve as a new source of antimicrobials with potential applications and related health benefits

Prevalence of psychiatric illnesses after major limb amputation and early recognition and treatment in economically lower income group patients

Background: There is high prevalence of psychiatric illness after major limb amputation and need for early recognition and treatment should be the goal but often is overlooked. Psychological support by the treating physician and the surgeon can help in adaptation to the disability but unfortunately is often overlooked.Methods: A total of 120 patients were screened for psychiatric disorder using HADS criteria Anxiety was found to be in 38 (32%) patients and depression was found to be in 27 (23%) (Table 1) (Figure 1) 55 patients had no psychiatric illness. Psychiatric illness either depression or anxiety was found to be in 65 patients.Results: In our state which is a zone of conflict between two countries prevalence of anxiety was 32% and depressive symptoms were 23%, respectively. Causative factors associated with high prevalence of psychological symptoms included unmarried young females, lower socioeconomic status, single earning member, lack of social support, unemployment, traumatic amputation. These findings were confirmed by a significant reduction of anxiety and depression scores in patients who received social support, patients with amputation due to disease, and patients with above the knee amputation.Conclusions: Our study showed higher prevalence of psychological symptoms in association with lower socioeconomic status, single earning member, lack of social support, unemployment, traumatic amputation vs amputation secondary to chronic disease. Extensive rehabilitation with the use of an interdisciplinary team approach is one of the most successful ways to return the amputee to the work place. Surgeons should give proper attention to the psychological state of amputees. Because of high prevalence of psychiatric illness after major limb amputation. It is suggested that psychiatric evaluation and adequate rehabilitation should form a part of treatment

A call to action: Temporal trends of COVID-19 deaths in the South African Muslim community

No abstract

Outcomes of surgical management of liver trauma at LUMHS Jamshoro

Background: Mortality from liver trauma remains high despite surgical advancements. The objective of this study was to determine the outcomes of surgical management of liver trauma at LUMHS Jamshoro.Methods: A cross-sectional observational study using non-probability convenient sampling technique was done at department of surgery LUMHS Jamshoro for 18 months. Patients between 14 to 50 years with blunt hepatic trauma presenting to the E.R. within 04 hours of incident were included and hepatic trauma patients managed conservatively, having multiple trauma and hemo-dynamically stable were excluded. SPSS version 20 was used for data analysis with mean and SD reported for qualitative and frequency and percentages for quantitative variables. Chi-square test was applied keeping p-value of < 0.05 as statistically significant.Results: From 136 patients with mean age of 32.33±1.23 years, 120 (88%) were male. 122 (89.7%) were admitted due to blunt trauma and 14 (10.3%) due to penetrating trauma. Peri-hepatic packing was performed in 116 (85.2%) and suture hepatorrhaphy in 20 (14.8%). Intra-abdominal sepsis was seen in 41 (30%) of patients followed by recurrent hemorrhage in 33 (24%) while 30 (22%) of patients died. Substantial differences (p < 0.001) were observed in terms of surgical technique and each of the complication i.e. sepsis, bile leak and recurrent hemorrhage among alive patientsConclusions: The most common post-operative complication was intra-abdominal sepsis followed by recurrent haemorrhage and bile leak. Significant mortality was observed in between type of complication as well as surgical technique

Landslide Investigation at Phata Village on Rudraprayag-Kedarnath Road, Uttaranchal — A Case Study

Phata village on the Guptakashi-Gaurikund road in the Mandakini valley of Garhwal Himalaya was affected by a major landslide on 16th July 2001 due to heavy rainfall. The debris flow not only swept away several houses but it also claimed 15 lives. A detailed landslide investigation was carried out to assess the present stability condition. Geotechnical investigation was carried out to determine the soil properties. Seismic refraction survey to determine the overburden thickness was also carried out using Engineering Seismograph. Slope stability analysis was carried out to ascertain the existing stability of the slope. It was found that with rise in pore pressure the slope is marginally stable. The seismic stability analysis showed that seismicity of the order of 0.15g may trigger slips on the slope. The human settlement on the downhill slope may get effected in the eventuality of slide due to seismicity or rain. The paper presents the results of the geological and geotechnical studies which helped to assess the present stability condition